This is from here. I consider this the most important information for covid vaccine hesitant people to hear.
And let us recall the big boogeymen of failed vaccines past: using a completely different process over 60 years ago Cutter Labs failed to inactivate polio and just injected it straight into kids (i.e. a failure mode not physically possible with current technology), some weird autoimmune interactions in the 1970s gave us 1/100,000 rates of GBS (i.e. not even a rounding error in the Covid death toll), ADE in dengue vaccines in the Philippines (maybe, the official lookback could not definitely tell if a couple of dozen kids died from ADE induced by the vaccine or if that was just dengue being its normal malevolent self), and a small increase in bowel obstruction with rotavirus (1/12,000, only seen in one variant and not observed in other rotavirus vaccines). We could have had all of them in the Covid vaccines and they would still be an order of magnitude safer than the status quo. And they would still be an order of magnitude safer than the status quo for the under 50 crowd.
Yes, I get it, there is some tail risk that somewhere out there might be something new we have never seen before. I cannot tell you that I have absolutely zero uncertainty that something completely new will rear its ugly head here; but that same uncertainty exists for the status quo. Will lockdowns lead to delayed mental health issues? I don’t know, but the indicators I see right now are not pretty. Does shafting childrens’ educations for more and more months have lifelong impacts on things like suicide risk, IVDU, CAD, and the rest? Cannot say for certain, but I see no reason why it doesn’t unless you have an extremely dim view of education’s ability to impact on life outcomes. Delayed cancer screenings, deferred elective surgeries … the uncertainty in the NPIs easily dwarfs that of the vaccines.
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